Mounjaro, generically known as tirzepatide, is an innovative injectable medication approved for chronic weight management. As a dual GLP-1 and GIP receptor agonist, Mounjaro is designed to help adults with obesity or overweight conditions achieve significant weight loss while also managing blood sugar levels.

Mounjaro utilises a unique mechanism of action by activating both the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors. This dual action leads to:

• Reduced Appetite: Mounjaro helps decrease hunger signals in the brain, promoting a sense of fullness and reducing caloric intake.
• Enhanced Insulin Sensitivity: By improving the body’s response to insulin, Mounjaro helps regulate blood sugar levels effectively.
• Slowed Gastric Emptying: The medication slows the movement of food through the digestive system, further contributing to a prolonged feeling of fullness.

Mounjaro is intended for adults who:

• Have a body mass index (BMI) of 30 or greater (obesity)
• Have a BMI of 27 or greater (overweight) with at least one weight-related health issue (such as type 2 diabetes, high blood pressure, or high cholesterol)

Before starting Mounjaro, it is essential to consult your healthcare provider, or our pharmacist, to determine if this medication is appropriate for your weight management plan.

Mounjaro is administered as a subcutaneous injection, typically once a week. Our pharmacist will prescribe the right dosage based on your health profile and response to the treatment.

Typical Dosage Schedule:

1. Starting Dose: 2.5 mg weekly for the first month.
2. Titration: Gradually increase to 5 mg, then 7.5 mg, and up to 15 mg weekly as tolerated, if suitable.

Important: Always adhere to our pharmacist's recommendations regarding dosage and administration.

While Mounjaro can be effective for weight management, it may cause side effects in some individuals. Common side effects include:

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Abdominal pain

Serious side effects, although rare, can occur and may include pancreatitis, kidney problems, or severe allergic reactions. If you experience intense abdominal pain or any signs of an allergic reaction, seek medical help immediately.

For the best results with Mounjaro, it’s essential to combine the medication with healthy lifestyle changes:

• Diet: Focus on a balanced diet rich in fruits, vegetables, lean proteins, and whole grains.
• Exercise: Incorporate regular physical activity, aiming for at least 150 minutes of moderate exercise per week.
• Behavioral Support: Consider joining weight loss support groups or working with a registered dietitian to maintain motivation and accountability.

Is Mounjaro safe for long-term use?

Clinical studies have shown Mounjaro to be safe and effective for long-term use in weight management. Regular monitoring by your healthcare provider is essential.

Can I use Mounjaro if I have type 2 diabetes?

If you have type 2 diabetes your treatment plan and options should be discussed with your GP or diabetic practitioner.

What happens if I stop taking Mounjaro?

Weight management requires ongoing lifestyle changes. Discontinuing Mounjaro without adopting healthy habits may lead to weight regain.

Mounjaro (tirzepatide) represents a groundbreaking approach to weight management for individuals struggling with obesity or overweight. With its dual-action mechanism and potential for significant weight loss, it can play a crucial role in your weight loss journey. Book a consultation with our pharmacist to explore whether Mounjaro is the right option for your health needs.

For patients looking for reliable, UK-based resources about Mounjaro and its availability for weight management, here are a few links that provide relevant guidance and information:

1. NHS Obesity Treatment Guidelines: The NHS website outlines comprehensive treatment options for obesity, including Wegovy and other medications. This includes recommendations on lifestyle changes and considerations when using weight management medicines like semaglutide. For more details, visit NHS Obesity Treatment Guidelines

2. NICE Guidance on Semaglutide for Weight Management: The National Institute for Health and Care Excellence (NICE) provides in-depth guidance for healthcare professionals and patients regarding the use of semaglutide. It explains eligibility criteria, recommended duration of use, and advice on when to discontinue treatment if progress is insufficient. You can find this information on the NICE website

3. Mounjaro information website.